Animal Diseases and Surgery
Anatomy, Pharmacology and Hygiene
Veterinary Public Health
4. Meat Hygiene and Technology
5. LPT Milk

Poisoning

Poisoning 

  • Tentative
  • Presumptive
  • Confirmative

History

  • Poisoning was accidental Malicious

Physical Examination & Clinical Evidence

  1. Preservation of vital cl.  parameter I. E. Temp., pulse, respiration rate & blood pressure
  2. e. g. Organo-phosphorus comp – cause
  3. Hypothermia belladonna – hypothermia
  4. Odour, color, dryness is also noted for diff. Organ
  5. Pathological evidence
  6. Necropsy finding
  7. Gross & microscopic examination of tissue & organ.
  8. Analytical evidence
  9. Qualitative & quantitative detection of significant.
  10. Amount of toxic agent in biological sample i.e. Blood, faeces, vomitus, urine &adipose tissue.

Treatment

1) Prevention of G. l. T. Adsorption of toxin

      a) Removal of poison from stomach

  • gastric lavage
  • emetic
  • Xylazine 1mg/kg. B. W. dog
  • Apomorphine hydrochloride
  • 0.04 – 0. 07 mg. / kg. B. W
  • 1/v, 1/m or s/c

     b) Fastening / quickly passage through bowl

     c) Neutralization of poison

  • Saline purgative
  • Activated charcoal (absorbing agent)
  • Neutralization agent
  • Acid, alkali
  • chelating agent e. g. EDTA

2) Facilitate Removal from body

  • gm. Glomerular filtration rate 10% glucose or 10%
  • Mannitol
  • Reduce tubular reabsorption
  • Change PH of urine
  • Acidic – Ammonium chloride, Ascorbic acid
  • Sodium acid phosphate
  • Alkalize – sodium bicarbonate, sodium acetate

Specific and non-specific Antagonist agents

   Non-specific agent

   1) Analeptic for barbiturate poisoning

   2) Vasopressors for hypotension

   3) Anticonvulsants for convulsive seizure

   4) Bronchodilator & Antihistamine – Anaphylactic Stock

Specific Antidote

1) Lead, mercury & Arsenic (AML)B. A. L ca. EDTA
2) CyanideSodium nitrate &Sodium thiosulfate
3) MolybdenumCopper
4) Organo phosphorusCholinesteraseReactivator(oximes)
Call Now Button