Lecture 3: Diagnosis and Treatment of Neurological diseases

PPT

Diagnosis and treatment of the neurological disorders Diagnosis

1) Clinical neurological examination

• Posture, gait and Behaviour of animal
• sensitivity
• Diminished (hyperaesthesia)
• Lost (Anaesthesia)
• Increased (hyperaesthesia)
• Anal reflex and tail reflex

2) Radiological examination

• To identify traumatised & congenital lesson or vertebral
• Column or skull
• contrast radiography is used

3) Used to screen lesions like tumour or in fact infracted changes in brain

4) Gamma emitter are scanned through scanner

5) Electro Encephalography (E. E. G)Record electrical activity of cerebral cortex

6) Nerve conduction velocity

7) blood glucose & B. U. N.  examination

8) C. S. T-shirt examination Lumbosacral or coccygeal – cattle

     a) C. S. T – pressure by spinal fluid manometer 105 ml H2o – cattle

     b)  physical properties Color, consistency, coagulability

     c)  chemical examination Glucose & protein

Meningitis (inflammation of pia & arachnoid membrane) and its Treatment

• 1) Sulpha diazine (drug of choice) Because it attains max. Concentration in C. S. T.  For 5-7days Chloramphenicol @ 4-10 mg / kg. B.W. it can cross B.B.B (blood brain barrier)
• 2) To check spasm Phenobarbitone (Anticonvulsant)  
• 3) To relieve intracranial pressure > mannitol 100 – 300 cc 1/v
• 4) Use of sedative & tranquilizers
• 5) Use of corticosteroids
• 6) Specific treatment for specific agent
• 7) Vit B1 / thiamine 5-10 mg / kg. B. W.

Epilepsy Treatment Guidelines for Therapy

• Max Dose given initially
• No drug should be with dream suddenly
• replacement of drug should do gradually
• more Dose given in evening rather than morning