Lesson Progress
0% Complete


Route of transmission

Direct contact, inhalation, conjunctiva acute course of disease with symptom of H.S.


Virus reaches blood airculation

Through nasopharynx & tonsil  


Multiply rapidly in blood


Invade vascular endothelium

& cause degenration


obliteration of their luman

as a resultof end arteritis


infarction & necrosis of spleen Kidney & intestine

Clinical finding

  • High rise of temp. & erythematous patches
  • Vomition, severe diarrhea (offensive)
  • Hyperemia of skin with purplish discolouration of snout, ear, abdomen & inner sides of legs
  • Peculiar blotching effect on ear (irregular spot)
  • Wobbing gait, ataxia, tremor, convulsion,
  • Still bird or abnormal piglet


  • Petechial & ecchmotic haemorrhage in all serous surface (pleura, peritoneum)
  • Liver is dark, congested
  • Turkey egg appearance of kidney removel  of capsule show button ulcer


  • Pathognomic PM lesion
  • Histopathological examination
  • Animal inoculation test
  • Gel diffusion precipitation test
  • C.F.T, HA, N.T., FAT


  1. Slaughter of affected animals, they should be buried & premises is properly disinfected
  2. All pig in form should kept under strict vigillance
  3. Restriction of movement of pig
  4. Vaccine


  •  Viral pncumonic lesion i.e. atelective or consolidated and dark red to purple red lung.
  • Bronchial & mediastinal lympnode are oedematious, pulmonary oedema
  • Generalized lymphadenopathy, hepatic congestion and pulmonary consolidation.

Diagnosis Tools

  1. Microbiological test / serological test
  2. Biochemical test (gm Vi C)
  3. Bio-technological test
  4. Biological test / cultural examination

Bio-Technological Test

  1. Determination of ucleic acid
  2. P.C.R.and real time PCR
  3. Restriction fragment length polymorphism (RFLP)
  4. D.N.A. prole and D.N.A.microarry technology
  5. Detection of protain
  6. Immunoblotting .PA GE
  7. ELISA
  8. Antibody detection
  9. Competitive ELISA, serological test
  10. Nanotechnology